PRSice is seperated into two main parts:

  1. PRSice executable

    Responsible for the core algorithm

  2. PRSice Rscript

    Responsible for generating the bar-plot, high-resolution plot and quantile plot


PRS analysis can be performed using only the PRSice executable file (without the Rscript) with all non-plotting / R related parameters. This generates the PRS without plotting, which might be useful for those who are only interested in obtaining the PRS.

General Usage

usage: Rscript PRSice.R [options] \
    --base <base_file> \
    --target < target_file> \
    --prsice <prsice_location>

PRSice Binary (R specific)

  • --prsice

    Location of the PRSice executable.