PRSice is seperated into two main parts:

  1. PRSice executable

    Responsible for the core algorithm

  2. PRSice Rscript

    Responsible for generating the bar-plot, high-resolution plot and quantile plot


You can perform PRS analysis using only the PRSice executable file (without the Rscript) with all non-plotting / R related parameters. This allow you to generate the PRS without performing the plotting, which might be useful for users who are interested in only obtaining the PRS.

General Usage

usage: Rscript PRSice.R [options] \
    -b <base_file> \
    -t < target_file> \
    --prsice <prsice_location>

PRSice Binary (R specific)

  • --prsice

    inform the location of the PRSice executable.